Endocrine Abstracts

Introduction: The prevalence of thyroid diseases increase with age. Mostly, they are undiagnosed. The lack of overt clinical appearance of hypo-hyperthyroidism in elder people increases the need for an attentive clinician to suspect and investigate for their presence. Thyroid dysfunctions, especially subclinics, are more frequently seen in older populations, have been linked to increased morbidity and mortality. Therefore, elderly people should evaluate in terms of thyroid fun...

Langerhans cell histiocytosis (LCH) is a disease with monoclonal proliferation and infiltration of organs by Langerhans cell. LCH is commonly seen in the skeletal system and skin, but it may also involve paranchymal organs. Thyroid involvement in LCH is unusual, and coexistence of thyroid with lung involvement is seen very rare. Here we present a patient with LCH, who has thyroid and lung involvement.Case: A 26-old woman, who had LCH of the lung was refe...

Introduction: Although, vitamin D (vit D) mainly regulates calcium and phosphate metabolisms, its deficiency may also contribute to the development of some carcinomas, autoimmune, and cardiac diseases. Vit D deficiency has been defined to correlate with increased autoimmune disease such as type 1 diabetes mellitus, rheumatoid arthritis, autoimmune thyroid diseases (AITD). Previous studies suggested that patients with AITD had lower vit D levels when compared with healthy contr...

Objective: Long acting somatostatin analogs commonly used as adjuvant treatment of acromegalic patients after noncurative surgery. We aimed to compare the efficacy of octreotide LAR (OCT) and lanreotide Autogel (LAN) in acromegalic patients.Methods: Sixty-eight patients that cure could not be achieved by transsfenoidal endoscopic or microscopic pituitary surgery between 2003 and 2009 were retrospectively analyzed (25 men and 43 women; mean age 41.1±...

Objective: Hyperprolactinemia is the most common abnormality of the hypothalamic–pituitary axis. In the majority of patients with hyperprolactinemia monomeric prolactin (monoPRL) namely PRL with a molecular weight of 23 kDa predominates. But, in some patients with hyperprolactinemia high molecular weight forms of PRL namely macroprolactin (macroPRL) is detected. We aimed to investigate the clinic and radiologic features associated with the macroPRL....